You Can’t Win Alone

On Leadership, Purpose, And Collective Intelligence In Biomedical Innovation

Oct 17 • 

Sean Khozin, MD, MPH

5

Everything is Changing Everywhere

A conversation with investor, social entrepreneur, and patient advocate Daniel Arbess on why medicine needs institutional innovation, not just more…

Oct 15 • 

Sean Khozin, MD, MPH

3

September 2025

What Are We Spending Our Money On?

The trillion-dollar administrative state that ate American medicine

Sep 23 • 

Sean Khozin, MD, MPH

2

Precision Signals: James Gulley, MD, PhD

Endpoints, Resistance, and the Architecture of Evidence in Immuno-Oncology

Sep 4 • 

Sean Khozin, MD, MPH

3

August 2025

The Misnomer of Surrogate Endpoints in Oncology

An Examination of a Fundamental Flaw in Regulatory Language and Scientific Precision

Aug 20 • 

Sean Khozin, MD, MPH

4

Precision Signals: Episode 2, Michelle Longmire, MD

A conversation on science, risk-taking, and the discipline of innovation

Aug 19 • 

Sean Khozin, MD, MPH

5

New Podcast Series: Precision Signals, Episode 1 with Olivier Elemento, PhD and Cora Sternberg, MD

AI in Oncology: Promise, Evidence, and the Threshold of Trust

Aug 12 • 

Sean Khozin, MD, MPH

2

The Three Waves of AI in Biomedicine: From Promise to Proof

How the next inflection point will make adoption irreversible

Aug 11 • 

Sean Khozin, MD, MPH

4

July 2025

From Breakthrough to Breakdown: The $900 Million FDA Rejection Letter

FDA's RP1 Rejection Signals Regulatory Transformation

Jul 22 • 

Sean Khozin, MD, MPH

9

3

The End of Disciplinary Sovereignty

Rethinking Expertise in the Era of Algorithmic Intelligence

Jul 11 • 

Sean Khozin, MD, MPH

4

2

June 2025

Beyond Gold Standards: Sins of Omission and Sins of Commission

The Perils of Precedent in Scientific Inquiry

Jun 12 • 

Sean Khozin, MD, MPH

3

1

May 2025

AI and the Reclamation of Scientific Abstraction

Redefining the Objects of Scientific Inquiry

May 18 • 

Sean Khozin, MD, MPH

3

2