When the Cure Already Exists

A conversation with David Fajgenbaum on drug repurposing, rare disease, and why the answers might already be on the shelf

8 hrs ago • Sean Khozin, MD, MPH

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The Interoperability Illusion

How America Built a $36 Billion Digital Health Infrastructure That Can’t Talk to Itself

Feb 15 • Sean Khozin, MD, MPH

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Tracing the Signal Beneath the Noise

A Conversation with CEO of Replimune Sushil Patel on the Edge of Immunotherapy

Feb 10 • Sean Khozin, MD, MPH

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The Simulator’s Dilemma

Reflections on AI in Drug Discovery

Feb 4 • Sean Khozin, MD, MPH

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January 2026

The Ghost in the Statistical Machine and the Illusion of the Average Patient

A Brief History of Precision in Medicine and FDA's Evolution

Jan 26 • Sean Khozin, MD, MPH

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After the Fog Lifted

Reflections from JPMC 2026 on AI, GLP-1s, and the new physics of biopharma

Jan 19 • Sean Khozin, MD, MPH

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From Bench to Boardroom: Cancer, Capital, and System Design

A conversation with Dan McHugh, investor at Yosemite

Jan 16 • Sean Khozin, MD, MPH

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December 2025

Leading at Every Altitude

A conversation with Dr. Karen Knudsen on the science and business of cancer research and care

Dec 16, 2025 • Sean Khozin, MD, MPH

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November 2025

When the Rails Couldn’t Carry the Future

How biomedical infrastructure became the 1890s railroad

Nov 20, 2025 • Sean Khozin, MD, MPH

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October 2025

The Architecture of Cancer Research in Four Movements

Sustained foundations, emerging disruptions, future capabilities, and the work of translation

Oct 30, 2025 • Sean Khozin, MD, MPH

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You Can’t Win Alone

On Leadership, Purpose, And Collective Intelligence In Biomedical Innovation

Oct 17, 2025 • Sean Khozin, MD, MPH

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Everything is Changing Everywhere

A conversation with investor, social entrepreneur, and patient advocate Daniel Arbess on why medicine needs institutional innovation, not just more…

Oct 15, 2025 • Sean Khozin, MD, MPH

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